Intravenous lidocaine affects oxaliplatin pharmacokinetics in simultaneous infusion
نویسندگان
چکیده
منابع مشابه
Oxaliplatin pharmacokinetics during a four-hour infusion.
A new platin compound, oxaliplatin, has significant activity in advanced colorectal carcinomas. However, its pharmacokinetics have not been characterized adequately yet. This study extensively analyzes the pharmacokinetics of both ultrafiltrable (free) and protein-bound platin in 13 patients receiving 130 mg/m2 oxaliplatin as a 4-h infusion in combination with 375 mg/m2 5-fluorouracil as a 24-h...
متن کاملIntravenous lidocaine infusion for pain control after laparoscopic cholecystectomy
BACKGROUND This meta-analysis aimed to assess the efficiency and safety of intravenous infusion of lidocaine for pain management after laparoscopic cholecystectomy (LC). METHODS A systematic search was performed in PubMed (August 1966-2017), Medline (August 1966-2017), Embase (August 1980-2017), ScienceDirect (August 1985-2017), and the Cochrane Library. Only randomized controlled trials (RCT...
متن کاملIntravenous continuous infusion of lidocaine for treatment of equine ileus.
OBJECTIVE To determine if intravenous lidocaine is useful and safe as a treatment for equine ileus. STUDY DESIGN Prospective double-blinded placebo-controlled trial. STUDY POPULATION Horses (n = 32) with a diagnosis of postoperative ileus (POI) or enteritis and that had refluxed >20 L or had been refluxing for >24 hours. METHODS Refluxing horses were administered lidocaine (1.3 mg/kg intr...
متن کاملIntravenous lidocaine infusion facilitates acute rehabilitation after laparoscopic colectomy.
BACKGROUND Intravenous infusion of lidocaine decreases postoperative pain and speeds the return of bowel function. The authors therefore tested the hypothesis that perioperative lidocaine infusion facilitates acute rehabilitation protocol in patients undergoing laparoscopic colectomy. METHODS Forty patients scheduled to undergo laparoscopic colectomy were randomly allocated to receive intrave...
متن کاملAnalgesic Efficacy of Intravenous Lidocaine Infusion in Cesarean Section under Spinal Anesthesia: A Prospective Randomized Double-Blind Study
Background & Objective: Nowadays, conventional analgesic agents that are usually used for pain killing after cesarean sections do not provide enough analgesia with infrequent serious side effects. Lidocaine has been suggested as an adjuvant analgesic agent for postoperative pain relief. We designed this randomized double-blind, placebo-controlled study to evaluate the analgesic efficacy of intr...
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ژورنال
عنوان ژورنال: Journal of Oncology Pharmacy Practice
سال: 2020
ISSN: 1078-1552,1477-092X
DOI: 10.1177/1078155220905011